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kannst du das mit Toxopherese genauer erlaeutern? so wie ich es verstehe ist ja eine art blutwaesche, was jetzt ja bei einer chronischen cpn infektion bestenfalls zeitlich begrenzte ergebnisse erzielen kann durch das filtern von toxinen etc pp, oder verstehe ich das falsch?
hohes ldl ist bei einer chronischen cpn infektion immer ein problem, weil das das die bakterienreproduktion foerdert. betreffend arteriosklerose wird vermutet, dass cpn seinen beitrag durch oxidation von ldl leistet, was ja dann auf dauer auch zum problem wird.
Virtually all patients that I diagnose with chronic persitent Cpn (Chlamydophila pneumoniae) infection have a raised LDL level. If they are treated with a statin from the begining, they will frequently have typical muscle and joint symptoms. If however they are commenced on the appropriate antibiotic protocol and diet first, then recheck their LDL level, it usually reduces a little, perhaps enough to get to the level I am after. If it doesn’t reduce enough – often it is quite high, I commence them on a low dose of rosuvastatin and they don’t get the statin side effects. At that stage many get by with a low dose of statin. If they respond well to the treatment and I have evidence that the Cpn infection has been eliminated or suppressed enough, they can come off the statin. So the statin is acting like an antibiotic. Cpn needs cholesterol for its outer membrane but can’t manufacture it itself. It has genes to manipulate human cholesterol metabolism in the liver (stops its secretion) and also oxidises LDL in circulating macrophages. This is one of the mechanisms by which it contributes to vascular disease. The other mechanism is its ability to increase platelet aggregation. Cpn is transmitted from person to person by prolonged close contact and this is why one sees high prevalence in situations such as army barracks. However, I suspect the main transmission comes from within the family and may be the reason why many diseases appear to have a “genetic” – you catch it off your parents. It is of interest that the neurologists are now trailing the use of statins in MS! Unfortunately they just understand why statins may be of beenfit in this situation.” Dr Paul Thibault (in conversation with science journality Maryanne Demasi), vascular specialist, Facebook, Australia, Apr 2019.
